Weight Loss, Set Point Theory, Metabolism and Thyroid Hormone

Do adaptive changes in metabolic rate favor weight regain in weight-reduced individuals? An examination of the set-point theory. Weinsier RL, Nagy TR, Hunter GR, Darnell BE, Hensrud DD, Weiss HL. Am J Clin Nutr. 2000 Nov;72(5):1088-94. [FREE FULL TEXT] From the study: Abstract BACKGROUND: Obese persons generally regain lost weight, suggesting that adaptive metabolic changes favor return … Read more

Intermittent Fasting Maintains Muscle when Dieting

Intermittent versus daily calorie restriction: which diet regimen is more effective for weight loss? Varady KA. Obes Rev. 2011 Jul;12(7):e593-601. [FREE FULL TEXT] Abstract Dietary restriction is an effective strategy for weight loss in obese individuals. The most common form of dietary restriction implemented is daily calorie restriction (CR), which involves reducing energy by 15-60% … Read more

Short Term Fasting Increases Metabolic Rate

Resting energy expenditure in short-term starvation is increased as a result of an increase in serum norepinephrine. Zauner C, Schneeweiss B, Kranz A, Madl C, Ratheiser K, Kramer L, Roth E, Schneider B, Lenz K. Am J Clin Nutr. 2000 Jun;71(6):1511-5. [free full text] Abstract BACKGROUND: The effects of food restriction on energy metabolism have been under … Read more

Intermittent Fasting and/vs Calorie Restriction Diets

Intermittent fasting dissociates beneficial effects of dietary restriction on glucose metabolism and neuronal resistance to injury from calorie intake. Anson RM1, Guo Z, de Cabo R, Iyun T, Rios M, Hagepanos A, Ingram DK, Lane MA, Mattson MP. Proc Natl Acad Sci U S A. 2003 May 13;100(10):6216-20. Epub 2003 Apr 30. Abstract Dietary restriction … Read more