Cold Laser, Low Level Laser, Anodyne… Bogus for Neuropathy

Does anodyne light therapy improve peripheral neuropathy in diabetes? A double-blind, sham-controlled, randomized trial to evaluate monochromatic infrared photoenergy. Lavery LA, Murdoch DP, Williams J, Lavery DC. Diabetes Care. 2008 Feb;31(2):316-21. Abstract OBJECTIVE: The purpose of this study was to determine the efficacy of anodyne monochromatic infrared photo energy (MIRE) in-home treatments over a 90-day period … Read more

Calorie Restriction Prevents Peripheral Nerve Damage

Lifelong calorie restriction alleviates age-related oxidative damage in peripheral nerves. Opalach K1, Rangaraju S, Madorsky I, Leeuwenburgh C, Notterpek L. Rejuvenation Res. 2010 Feb;13(1):65-74.  Abstract Aging is associated with protein damage and imbalance in redox status in a variety of cells and tissues, yet little is known about the extent of age-related oxidative stress in the peripheral … Read more

EMS Decreases Pain, Numbness, Burning, and Improves Sleep with Neuropathy

External electric muscle stimulation improves burning sensations and sleeping disturbances in patients with type 2 diabetes and symptomatic neuropathy.  Pain Med. 2009 Mar;10(2):413-9.  Humpert PM, Morcos M, Oikonomou D, Schaefer K, Hamann A, Bierhaus A, Schilling T, Nawroth PP. OBJECTIVE: External muscle stimulation (EMS) of the thighs was previously shown to have beneficial effects in … Read more

Electric Muscle Stimulation Better than TENS for Neuropathy

Effective treatment of symptomatic diabetic polyneuropathy by high-frequency external muscle stimulation. Diabetologia. 2005 May;48(5):824-8.  Reichstein L, Labrenz S, Ziegler D, Martin S. Abstract AIMS/HYPOTHESIS: Diabetic distal symmetrical sensory polyneuropathy (DSP) affects 20-30% of diabetic patients. Transcutaneous electrical nerve stimulation (TENS) and electrical spinal cord stimulation have been proposed as physical therapies. We performed a controlled, … Read more

Electric Stimulation Complementary with Drug Treatment for Neuropathy

Diabetic peripheral neuropathy. Effectiveness of electrotherapy and amitriptyline for symptomatic relief. Diabetes Care. 1998 Aug;21(8):1322-5. Kumar D, Alvaro MS, Julka IS, Marshall HJ. From the study: Abstract OBJECTIVE: To evaluate the efficacy of combining electrotherapy with amitriptyline for the management of chronic painful peripheral neuropathy in patients with type 2 diabetes. RESEARCH DESIGN AND METHODS: … Read more

Electric Stimulation Decreases/Eliminates Painful Neuropathy

  Diabetic peripheral neuropathy: amelioration of pain with transcutaneous electrostimulation. Diabetes Care. 1997 Nov;20(11):1702-5. Kumar D, Marshall HJ. Abstract OBJECTIVE: To evaluate the efficacy of transcutaneous electrotherapy for chronic painful peripheral neuropathy in patients with type 2 diabetes. RESEARCH DESIGN AND METHODS: Thirty-one patients with symptoms and signs of peripheral neuropathy were randomized to the … Read more