Are Dietitians Wrong About Dinner Time?

OK, are dietitians wrong about dinner time? I’m about to reinterpret some 20 year old research, which really got me thinking. Though I might be mistaken, I think the experts are wrong, and the research is on my side. Such that the oft made recommendation to have or finish dinner around 6 pm is not, … Read more

Intermittent Fasting, BDNF, Depression, More

Dietary restriction stimulates BDNF production in the brain and thereby protects neurons against excitotoxic injury. Duan W, Lee J, Guo Z, Mattson MP. J Mol Neurosci. 2001 Feb;16(1):1-12. [FREE FULL TEXT] AbstractDietary restriction (DR) increases the lifespan of rodents and increases their resistance to several different age-related diseases including cancer and diabetes. Beneficial effects of … Read more

Exercise vs Intermittent Fasting for Longevity

Differential effects of intermittent feeding and voluntary exercise on body weight and lifespan in adult rats. Goodrick CL, Ingram DK, Reynolds MA, Freeman JR, Cider NL. J Gerontol. 1983 Jan;38(1):36-45. AbstractMale wistar rats were housed in laboratory cages or activity-wheel cages at eight 10.5 or 18 months of age. Part of each cage group continued … Read more

Intermittent Fasting and Circadian Rhythms

I had a blog idea comparing various cleansing/detoxification schemes with intermittent fasting, with the gist being that there are some similarities. Both probably make you feel better for largely the same reasons, but that fasting is better and free. With detoxing and cleansing, it seems that someone is always trying to separate you from your … Read more

Intermittent Fasting Improves Heart Attack Survival, A LOT!

Anyone familiar with my blog, or me, will know that I have a pretty fair obsession with intermittent fasting for what are becoming more reasons than I can easily count. So what is particularly interesting about this paper, contrary to other papers where they have animals or people start fasting to prevent problems, this one … Read more

Intermittent Fasting Maintains Muscle when Dieting

Intermittent versus daily calorie restriction: which diet regimen is more effective for weight loss? Varady KA. Obes Rev. 2011 Jul;12(7):e593-601. [FREE FULL TEXT] AbstractDietary restriction is an effective strategy for weight loss in obese individuals. The most common form of dietary restriction implemented is daily calorie restriction (CR), which involves reducing energy by 15-60% of … Read more

Vegans vs Lacto-Ovo vs Pescetarians

Mortality in vegetarians and nonvegetarians: detailed findings from a collaborative analysis of 5 prospective studies. Key TJ, Fraser GE, Thorogood M, Appleby PN, Beral V, Reeves G, Burr ML, Chang-Claude J, Frentzel-Beyme R, Kuzma JW, Mann J, McPherson K. Am J Clin Nutr. 1999 Sep;70(3 Suppl):516S-524S. [FREE FULL TEXT] AbstractWe combined data from 5 prospective … Read more

Short Term Fasting Increases Metabolic Rate

Resting energy expenditure in short-term starvation is increased as a result of an increase in serum norepinephrine. Zauner C, Schneeweiss B, Kranz A, Madl C, Ratheiser K, Kramer L, Roth E, Schneider B, Lenz K. Am J Clin Nutr. 2000 Jun;71(6):1511-5. [free full text] AbstractBACKGROUND:The effects of food restriction on energy metabolism have been under investigation for … Read more

Intermittent Fasting (16/8) Improves Stroke Recovery

Intermittent fasting attenuates increases in neurogenesis after ischemia and reperfusion and improves recovery. Manzanero S, Erion JR, Santro T, Steyn FJ, Chen C, Arumugam TV, Stranahan AM. J Cereb Blood Flow Metab. 2014 May;34(5):897-905 [FREE FULL TEXT] AbstractIntermittent fasting (IF) is neuroprotective across a range of insults, but the question of whether extending the interval … Read more

Calorie Restriction Prevents Peripheral Nerve Damage

Lifelong calorie restriction alleviates age-related oxidative damage in peripheral nerves. Opalach K1, Rangaraju S, Madorsky I, Leeuwenburgh C, Notterpek L. Rejuvenation Res. 2010 Feb;13(1):65-74.  AbstractAging is associated with protein damage and imbalance in redox status in a variety of cells and tissues, yet little is known about the extent of age-related oxidative stress in the peripheral nervous … Read more

Intermittent Fasting Types and Terminology

Intermittent Fasting and Human Metabolic Health. Patterson RE, Laughlin GA, Sears DD, LaCroix AZ, Marinac C, Gallo LC, Hartman SJ, Natarajan L, Senger CM, Martínez ME, Villaseñor A. Journal of the Academy of Nutrition and Dietetics. 2015 Apr 6. My comments: I usually read several papers a day and try to find time to blog … Read more

Intermittent Fasting and/vs Calorie Restriction Diets

Intermittent fasting dissociates beneficial effects of dietary restriction on glucose metabolism and neuronal resistance to injury from calorie intake. Anson RM1, Guo Z, de Cabo R, Iyun T, Rios M, Hagepanos A, Ingram DK, Lane MA, Mattson MP. Proc Natl Acad Sci U S A. 2003 May 13;100(10):6216-20. Epub 2003 Apr 30. AbstractDietary restriction has … Read more

Decreasing Calories 30% Increases Testosterone 21-27%

Impact of moderate calorie restriction on testicular morphology and endocrine function in adult rhesus macaques (Macaca mulatta). Sitzmann BD, Brown DI, Garyfallou VT, Kohama SG, Mattison JA, Ingram DK, Roth GS, Ottinger MA, Urbanski HF. Age (Dordr). 2014 Feb;36(1):183-97. Abstract:We previously reported that moderate calorie restriction (CR) has minimal impact on testicular gene expression in … Read more