Do adaptive changes in metabolic rate favor weight regain in weight-reduced individuals? An examination of the set-point theory. Weinsier RL, Nagy TR, Hunter GR, Darnell BE, Hensrud DD, Weiss HL. Am J Clin Nutr. 2000 Nov;72(5):1088-94. [FREE FULL TEXT] From the study: AbstractBACKGROUND:Obese persons generally regain lost weight, suggesting that adaptive metabolic changes favor return to a … Read more
Intermittent versus daily calorie restriction: which diet regimen is more effective for weight loss? Varady KA. Obes Rev. 2011 Jul;12(7):e593-601. [FREE FULL TEXT] AbstractDietary restriction is an effective strategy for weight loss in obese individuals. The most common form of dietary restriction implemented is daily calorie restriction (CR), which involves reducing energy by 15-60% of … Read more
Intermittent fasting attenuates increases in neurogenesis after ischemia and reperfusion and improves recovery. Manzanero S, Erion JR, Santro T, Steyn FJ, Chen C, Arumugam TV, Stranahan AM. J Cereb Blood Flow Metab. 2014 May;34(5):897-905 [FREE FULL TEXT] AbstractIntermittent fasting (IF) is neuroprotective across a range of insults, but the question of whether extending the interval … Read more
Lifelong calorie restriction alleviates age-related oxidative damage in peripheral nerves. Opalach K1, Rangaraju S, Madorsky I, Leeuwenburgh C, Notterpek L. Rejuvenation Res. 2010 Feb;13(1):65-74. AbstractAging is associated with protein damage and imbalance in redox status in a variety of cells and tissues, yet little is known about the extent of age-related oxidative stress in the peripheral nervous … Read more
Intermittent Fasting and Human Metabolic Health. Patterson RE, Laughlin GA, Sears DD, LaCroix AZ, Marinac C, Gallo LC, Hartman SJ, Natarajan L, Senger CM, Martínez ME, Villaseñor A. Journal of the Academy of Nutrition and Dietetics. 2015 Apr 6. My comments: I usually read several papers a day and try to find time to blog … Read more
Intermittent fasting dissociates beneficial effects of dietary restriction on glucose metabolism and neuronal resistance to injury from calorie intake. Anson RM1, Guo Z, de Cabo R, Iyun T, Rios M, Hagepanos A, Ingram DK, Lane MA, Mattson MP. Proc Natl Acad Sci U S A. 2003 May 13;100(10):6216-20. Epub 2003 Apr 30. AbstractDietary restriction has … Read more
Impact of moderate calorie restriction on testicular morphology and endocrine function in adult rhesus macaques (Macaca mulatta). Sitzmann BD, Brown DI, Garyfallou VT, Kohama SG, Mattison JA, Ingram DK, Roth GS, Ottinger MA, Urbanski HF. Age (Dordr). 2014 Feb;36(1):183-97. Abstract:We previously reported that moderate calorie restriction (CR) has minimal impact on testicular gene expression in … Read more