Differential effects of intermittent feeding and voluntary exercise on body weight and lifespan in adult rats. Goodrick CL, Ingram DK, Reynolds MA, Freeman JR, Cider NL. J Gerontol. 1983 Jan;38(1):36-45. AbstractMale wistar rats were housed in laboratory cages or activity-wheel cages at eight 10.5 or 18 months of age. Part of each cage group continued … Read more
Creatine supplementation during resistance training in older adults-a meta-analysis. Devries MC, Phillips SM. Med Sci Sports Exerc. 2014 Jun;46(6):1194-203. AbstractINTRODUCTION:Age-related sarcopenia and dynapenia have negative effects on strength and the ability to perform activities of daily living. Resistance training (RT) increases muscle mass and strength in older adults and is an established countermeasure for sarcopenia … Read more
Intermittent fasting dissociates beneficial effects of dietary restriction on glucose metabolism and neuronal resistance to injury from calorie intake. Anson RM1, Guo Z, de Cabo R, Iyun T, Rios M, Hagepanos A, Ingram DK, Lane MA, Mattson MP. Proc Natl Acad Sci U S A. 2003 May 13;100(10):6216-20. Epub 2003 Apr 30. AbstractDietary restriction has … Read more
Impact of moderate calorie restriction on testicular morphology and endocrine function in adult rhesus macaques (Macaca mulatta). Sitzmann BD, Brown DI, Garyfallou VT, Kohama SG, Mattison JA, Ingram DK, Roth GS, Ottinger MA, Urbanski HF. Age (Dordr). 2014 Feb;36(1):183-97. Abstract:We previously reported that moderate calorie restriction (CR) has minimal impact on testicular gene expression in … Read more
Sarcopenia: the role of apoptosis and modulation by caloric restriction. Dirks Naylor AJ, Leeuwenburgh C. Exerc Sport Sci Rev. 2008 Jan;36(1):19-24. AbstractThe mechanisms of sarcopenia have been slowly unraveled and likely involve activation of apoptosis. It is hypothesized that caloric restriction may, in part, attenuate sarcopenia by affecting apoptotic signaling. The signaling pathways responsible for … Read more
Always looking for something for nothing, this might be the ultimate. When I was a competitive bodybuilder and weightlifter I was always force feeding myself to gain weight and compete in higher weight classes, and as fun as that sounds it gets old. In the last few years I had been vaguely following the results … Read more