I was over at a buddy’s house when he opened some mail, and in it was Michael Mosley’s new book The 8-Week Blood Sugar Diet. I was like, “Oh that’s the 5:2 guy, he’s cool he’s into intermittent fasting.” At the time I was familiar with Dr. Moseley from having watched his video on intermittent … Read more
OK, are dietitians wrong about dinner time? I’m about to reinterpret some 20 year old research, which really got me thinking. Though I might be mistaken, I think the experts are wrong, and the research is on my side. Such that the oft made recommendation to have or finish dinner around 6 pm is not, … Read more
Dietary restriction stimulates BDNF production in the brain and thereby protects neurons against excitotoxic injury. Duan W, Lee J, Guo Z, Mattson MP. J Mol Neurosci. 2001 Feb;16(1):1-12. [FREE FULL TEXT] AbstractDietary restriction (DR) increases the lifespan of rodents and increases their resistance to several different age-related diseases including cancer and diabetes. Beneficial effects of … Read more
Differential effects of intermittent feeding and voluntary exercise on body weight and lifespan in adult rats. Goodrick CL, Ingram DK, Reynolds MA, Freeman JR, Cider NL. J Gerontol. 1983 Jan;38(1):36-45. AbstractMale wistar rats were housed in laboratory cages or activity-wheel cages at eight 10.5 or 18 months of age. Part of each cage group continued … Read more
Do adaptive changes in metabolic rate favor weight regain in weight-reduced individuals? An examination of the set-point theory. Weinsier RL, Nagy TR, Hunter GR, Darnell BE, Hensrud DD, Weiss HL. Am J Clin Nutr. 2000 Nov;72(5):1088-94. [FREE FULL TEXT] From the study: AbstractBACKGROUND:Obese persons generally regain lost weight, suggesting that adaptive metabolic changes favor return to a … Read more
I had a blog idea comparing various cleansing/detoxification schemes with intermittent fasting, with the gist being that there are some similarities. Both probably make you feel better for largely the same reasons, but that fasting is better and free. With detoxing and cleansing, it seems that someone is always trying to separate you from your … Read more
Anyone familiar with my blog, or me, will know that I have a pretty fair obsession with intermittent fasting for what are becoming more reasons than I can easily count. So what is particularly interesting about this paper, contrary to other papers where they have animals or people start fasting to prevent problems, this one … Read more
For those of you who don’t like to read, this blog about intermittent fasting educational videos is for you. I have been doing intermittent fasting for 6 months now, and I have a number of comments to add since making my observations after my first 40 plus days. Since the initial 40 days, I basically … Read more
Creatine supplementation during resistance training in older adults-a meta-analysis. Devries MC, Phillips SM. Med Sci Sports Exerc. 2014 Jun;46(6):1194-203. AbstractINTRODUCTION:Age-related sarcopenia and dynapenia have negative effects on strength and the ability to perform activities of daily living. Resistance training (RT) increases muscle mass and strength in older adults and is an established countermeasure for sarcopenia … Read more
Coffee and tea: perks for health and longevity? Bhatti SK1, O’Keefe JH, Lavie CJ. Curr Opin Clin Nutr Metab Care. 2013 Nov;16(6):688-97. [FREE FULL TEXT] From the Abstract:RECENT FINDINGS:Tea consumption, especially green tea, is associated with significantly reduced risks for stroke, diabetes, depression, and improved levels of glucose, cholesterol, abdominal obesity and blood pressure. Habitual coffee … Read more
Intermittent versus daily calorie restriction: which diet regimen is more effective for weight loss? Varady KA. Obes Rev. 2011 Jul;12(7):e593-601. [FREE FULL TEXT] AbstractDietary restriction is an effective strategy for weight loss in obese individuals. The most common form of dietary restriction implemented is daily calorie restriction (CR), which involves reducing energy by 15-60% of … Read more
Alcohol dosing and total mortality in men and women: an updated meta-analysis of 34 prospective studies. Arch Intern Med. 2006 Dec 11-25;166(22):2437-45. Di Castelnuovo A, Costanzo S, Bagnardi V, Donati MB, Iacoviello L, de Gaetano G. [FREE FULL TEXT] AbstractBACKGROUND:Moderate consumption of alcohol is inversely related with coronary disease, but its association with mortality is … Read more
Alcohol consumption, weight gain, and risk of becoming overweight in middle-aged and older women. Wang L, Lee IM, Manson JE, Buring JE, Sesso HD. Arch Intern Med. 2010 Mar 8;170(5):453-61. [FREE FULL TEXT] AbstractBACKGROUND:The obesity epidemic is a major health problem in the United States. Alcohol consumption is a source of energy intake that may contribute to … Read more
Does resistance training improve the functional capacity and well being of very young anorexic patients? A randomized controlled trial. del Valle MF, Pérez M, Santana-Sosa E, Fiuza-Luces C, Bustamante-Ara N, Gallardo C, Villaseñor A, Graell M, Morandé G, Romo GR, López-Mojares LM,Ruiz JR, Lucía A. J Adolesc Health. 2010 Apr;46(4):352-8. AbstractPURPOSE:We determined the effects of … Read more
Mortality in vegetarians and nonvegetarians: detailed findings from a collaborative analysis of 5 prospective studies. Key TJ, Fraser GE, Thorogood M, Appleby PN, Beral V, Reeves G, Burr ML, Chang-Claude J, Frentzel-Beyme R, Kuzma JW, Mann J, McPherson K. Am J Clin Nutr. 1999 Sep;70(3 Suppl):516S-524S. [FREE FULL TEXT] AbstractWe combined data from 5 prospective … Read more
Resistance training enhances muscular performance in patients with anorexia nervosa: a randomized controlled trial. Fernandez-del-Valle M, Larumbe-Zabala E, Villaseñor-Montarroso A, Cardona Gonzalez C, Diez-Vega I, Lopez Mojares LM, Perez Ruiz M. International Journal of Eating Disorders 2014 Sep;47(6):601-9. From the Abstract METHODS:From a total of 36 female patients with AN-R, one group (intervention, n = 18) underwent a … Read more
Resting energy expenditure in short-term starvation is increased as a result of an increase in serum norepinephrine. Zauner C, Schneeweiss B, Kranz A, Madl C, Ratheiser K, Kramer L, Roth E, Schneider B, Lenz K. Am J Clin Nutr. 2000 Jun;71(6):1511-5. [free full text] AbstractBACKGROUND:The effects of food restriction on energy metabolism have been under investigation for … Read more
Actually it was 43 days before I got my blood test and 47 days before I finally cheated. My plan at first was 30 days, then figured who fasts for 30 days? 40 days has more history, then I figured I’d try to do at least one more day than Jesus, then I had to … Read more
Intermittent fasting attenuates increases in neurogenesis after ischemia and reperfusion and improves recovery. Manzanero S, Erion JR, Santro T, Steyn FJ, Chen C, Arumugam TV, Stranahan AM. J Cereb Blood Flow Metab. 2014 May;34(5):897-905 [FREE FULL TEXT] AbstractIntermittent fasting (IF) is neuroprotective across a range of insults, but the question of whether extending the interval … Read more
Lifelong calorie restriction alleviates age-related oxidative damage in peripheral nerves. Opalach K1, Rangaraju S, Madorsky I, Leeuwenburgh C, Notterpek L. Rejuvenation Res. 2010 Feb;13(1):65-74. AbstractAging is associated with protein damage and imbalance in redox status in a variety of cells and tissues, yet little is known about the extent of age-related oxidative stress in the peripheral nervous … Read more
Intermittent Fasting and Human Metabolic Health. Patterson RE, Laughlin GA, Sears DD, LaCroix AZ, Marinac C, Gallo LC, Hartman SJ, Natarajan L, Senger CM, Martínez ME, Villaseñor A. Journal of the Academy of Nutrition and Dietetics. 2015 Apr 6. My comments: I usually read several papers a day and try to find time to blog … Read more
Intermittent fasting dissociates beneficial effects of dietary restriction on glucose metabolism and neuronal resistance to injury from calorie intake. Anson RM1, Guo Z, de Cabo R, Iyun T, Rios M, Hagepanos A, Ingram DK, Lane MA, Mattson MP. Proc Natl Acad Sci U S A. 2003 May 13;100(10):6216-20. Epub 2003 Apr 30. AbstractDietary restriction has … Read more
Impact of moderate calorie restriction on testicular morphology and endocrine function in adult rhesus macaques (Macaca mulatta). Sitzmann BD, Brown DI, Garyfallou VT, Kohama SG, Mattison JA, Ingram DK, Roth GS, Ottinger MA, Urbanski HF. Age (Dordr). 2014 Feb;36(1):183-97. Abstract:We previously reported that moderate calorie restriction (CR) has minimal impact on testicular gene expression in … Read more
Sarcopenia: the role of apoptosis and modulation by caloric restriction. Dirks Naylor AJ, Leeuwenburgh C. Exerc Sport Sci Rev. 2008 Jan;36(1):19-24. AbstractThe mechanisms of sarcopenia have been slowly unraveled and likely involve activation of apoptosis. It is hypothesized that caloric restriction may, in part, attenuate sarcopenia by affecting apoptotic signaling. The signaling pathways responsible for … Read more
Always looking for something for nothing, this might be the ultimate. When I was a competitive bodybuilder and weightlifter I was always force feeding myself to gain weight and compete in higher weight classes, and as fun as that sounds it gets old. In the last few years I had been vaguely following the results … Read more